FIGURE
Fig. 5
Fig. 5
Reduced ventricular CMs differentiate at the arterial pole of RA-deficient embryos. (A-B″) DMSO- and DEAB-treated myl7:nls-KikGR embryos at 48 hpf. Embryos were photoconverted at 24 hpf. Dashed line demarcates the border between green-only and green+/red + ventricular CMs. Views are lateral with the arterial pole up. Scale bars – 100 μm. (C) Quantification of the number of green-only cells within the ventricle. ∗∗∗∗ indicates p < 0.0001. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 473, Duong, T.B., Holowiecki, A., Waxman, J.S., Retinoic acid signaling restricts the size of the first heart field within the anterior lateral plate mesoderm, 119-129, Copyright (2021) with permission from Elsevier. Full text @ Dev. Biol.