FIGURE

Fig. 1

ID

ZDB-FIG-210406-16

Publication

Wang et al., 2020 - Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic-Acute Kidney Injury In Vivo

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Fig. 1

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Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB AB + CRISPR1-gsdmea AB + CRISPR2-casp3a AB + CRISPR2-gsdmea AB + CRISPR2-gsdmeb AB + CRISPR3-casp3a AB + CRISPR3-gsdmea AB + CRISPR4-casp3a AB + CRISPR4-caspb AB + CRISPR4-gsdmea AB + CRISPR5-casp3a AB + CRISPR5-pycard AB + CRISPR6-pycard AB + CRISPR7-pycard AB + CRISPR8-pycard
Condition:	chemical treatment by environment: 1-acyl-sn-glycero-3-phosphoserine
Knockdown Reagents:	CRISPR1-gsdmea CRISPR2-casp3a CRISPR2-gsdmea CRISPR2-gsdmeb CRISPR3-casp3a CRISPR3-gsdmea CRISPR4-casp3a CRISPR4-caspb CRISPR4-gsdmea CRISPR5-casp3a CRISPR5-pycard CRISPR6-pycard CRISPR7-pycard CRISPR8-pycard
Observed In:	caudal fin pericardium whole organism
Stage Range:	Day 5 to Days 7-13

Phenotype Detail

Acknowledgments

Full text @ J. Immunol.