Figure 5
- ID
- ZDB-FIG-210226-5
- Publication
- Abreu et al., 2020 - Circulating Tumor Cells Characterization Revealed TIMP1 as a Potential Therapeutic Target in Ovarian Cancer
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Effect of TIMP1 knock-down in SKOV3 proliferation in zebrafish embryos. (A) Representative images of the injected embryos with the different conditions of the TIMP1 silenced cells (SH3 and SH4) and the control cell line (PLKO) at 4 dpi and 6 dpi compared to 1 dpi. Main images are a superposition of a fluorescence image and a bright field image of the same embryo. Fluorescence images are a magnification of the areas marked in the main image. Scale = 250 µm. (B) Normalized tumor growth at 4 dpi (left panel): SKOV3_PLKO = 1.00, SKOV3_SH3=0.6072, SKOV3_SH4=0,6898; and 6 dpi (right panel): SKOV3_PLKO = 1.00, SKOV3_SH3 = 0.6155, SKOV3_SH4 = 0.8484 (nreplica = 15 embryos/condition, ntotal = 45 embryos/condition; * p < 0.05 according to two-sided T-test). |