Figure 1

Zebrafish lateral-line neuromasts. (A) Schematic depicts a larval zebrafish. Pink patches indicate the location of hair cells in the inner ear required for hearing and balance, as well as hair cells in the lateral-line system. Green patches represent the location of the anterior and posterior lateral-line ganglia. The cell bodies of neurons in these ganglia project to and innervate hair cells in the lateral line. (B) A side view of the anatomy of a single lateral-line neuromast. Hair cells (pink) are surrounded by supporting cells (internal, blue and peripheral, orange) and innervated by both afferent (green) and efferent neurons. Mechanosensory hair bundles (purple) at the apex of hair cells project out into the water to detect local water flow. Mitochondria (yellow, orange) make up dynamic tubular networks within hair cells. Adapted from Kindt and Sheets (2018).