FIGURE

FIGURE 5

ID
ZDB-FIG-210113-37
Publication
Langenbacher et al., 2020 - Mitochondrial Calcium Uniporter Deficiency in Zebrafish Causes Cardiomyopathy With Arrhythmia
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FIGURE 5

Analysis on cardiac arrhythmia in MCU mutant. (A) Increased heartbeat variability in MCU mutants displayed via Poincaré plots of consecutively occurring P-P intervals in adult wildtype and MCU mutant fish. (B) Summary of ECG data from 14 wildtype fish and 14 MCU mutant fish. Different cut-offs of P-P intervals were used to classify severity and definitive of occurring sinoatrial block episodes. Increased sample percentage with SA block episodes, per minute frequency, and consecutively occurring episodes were identified in MCU mutant (compared to wildtype), and further emphasized in MCU Class II mutants.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Adult

Phenotype Detail
Acknowledgments
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