ZFIN ID: ZDB-FIG-201209-4
Podobnik et al., 2020 - Evolution of the potassium channel gene Kcnj13 underlies colour pattern diversification in Danio fish. Nature communications   11:6230 Full text @ Nat. Commun.
Observed In:
Stage: Adult

Fig. 3 Mutant phenotypes in <italic>D. rerio</italic> and <italic>D. aesculapii</italic> of genes required for individual pigment cell types.

In D. rerio loss of one type of pigment cell type, a melanophores in Mitfa (nacre) mutants, c xanthophores in Csf1ra (pfeffer) mutants, or, e iridophores in Mpv17 (transparent) mutants, still permits rudimentary aggregation of dense iridophores (a) or melanophores (b, c). In D. aesculapii, loss of melanophores, b, in Mitfa mutants (n > 100) or loss of xanthophores, d, in Csf1ra mutants (n > 50), abrogate any residual pattern formation. However, vertical melanophore bars still form in Mpv17 mutants (n = 8), f despite the absence of iridophores. All images show representative examples of the corresponding genotypes. Scale bars correspond to 1 mm.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
csf1ratm236b/tm236b standard conditions Adult xanthophore absent, abnormal
mitfaw2/w2 standard conditions Adult iridophore absent, abnormal
slc24a5b6/b6 standard conditions Adult melanocyte absent, abnormal
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.