FIGURE

Figure 3

ID

ZDB-FIG-201102-21

Publication

Santhanam et al., 2020 - A Zebrafish Model of Retinitis Pigmentosa Shows Continuous Degeneration and Regeneration of Rod Photoreceptors

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Figure 3

Expression of P23H Flag-tagged rhodopsin in adult zebrafish retina. (A,B) The Flag-tagged P23H mutant rhodopsin (red) is expressed by sparsely-distributed photoreceptors in the adult fish (B); there is no labeling in wild type fish (A). (C,D) Mutant rhodopsin (red) colocalizes with rhodopsin (Retp1, green) in the rods. (E,F) Mutant rhodopsin (red) is expressed only by the rods and not the cones, as seen with the cone marker Zpr1 (green). Yellow arrowheads represent the cone axons and yellow arrows represent the cone myoids. ONL: outer nuclear layer; INL: inner nuclear layer; OS: outer segments. Scale bar in B applies to all panels.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	uth4Tg (AB)
Observed In:	retinal cone cell cone photoreceptor outer segment retinal rod cell rod photoreceptor outer segment
Stage:	Adult

Phenotype Detail

Acknowledgments

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