FIGURE
Figure 3
- ID
- ZDB-FIG-200817-33
- Publication
- Creusot et al., 2020 - The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor
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Figure 3
Dabrafenib binds to hPXR. Inhibition of FRET between fluorescein-labeled PXR ligand and recombinant GST-hPXR by SR12813 or dabrafenib. Results are expressed as the signal from the fluorescein emission divided by the terbium signal to provide a TR-FRET emission ratio. Data are the mean (±sd) from three independent experiments, *** |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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