FIGURE

Figure 2

ID

ZDB-FIG-200805-15

Publication

Chelladurai et al., 2020 - Isoform-specific characterization of class I histone deacetylases and their therapeutic modulation in pulmonary hypertension

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Figure 2

Immunolocalization of class I HDAC isoforms in human lungs from donors and IPAH patients. Representative microscopic pictures of human pulmonary arteries immunostained for (A) HDAC1, (B) HDAC2 and (C) HDAC8 expression in human donor and IPAH lung sections. HDAC (in green fluorescence) expression was localized to different vascular by staining for cell-specific markers such as von Willebrand factor (vWF, Red) for endothelial cells, α-smooth muscle actin (SMA or ACTA2, Red) for smooth muscle cells and collagen I (Col1 or COL1A1, Red) associated with adventitial fibroblasts, while the nucleus was counter-stained with DAPI (Blue). Scale bar: 50 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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