FIGURE

Fig. 6

ID

ZDB-FIG-200708-13

Publication

Wu et al., 2020 - Impaired oocyte maturation and ovulation in membrane progestin receptor (mPR) knockouts in zebrafish

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Fig. 6

Malformed embryos from in all seven membrane progestin receptor paralogues mutant (mprs−/−) females. (A–C) Reduced yolk size, chorion width, and the ratio of chorion size to yolk size in the mprs−/−embryos. 30% epiboly embryos were used (n = 7). (D) Representative malformed embryos (16-cell stage) from mprs−/− females with smaller yolk and chorion. (E) Disorganized and scrambled yolk granules on the surface of mprs−/− early stage embryo (32-cell stage embryo). a & b) wt; c & d) mprs−/−. Scale bars: a & c) 200 μm; b & d) 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	paqr5a^ecu14/ecu14; paqr5b^ecu15/ecu15; paqr6^ecu16/ecu16; paqr7b^ecu12/ecu12; paqr8^ecu13/ecu13; paqr9^ecu17/ecu17; paqr7a^ecu11/ecu11 (TU) paqr5a^ecu14; paqr5b^ecu15; paqr6^ecu16; paqr7b^ecu12; paqr8^ecu13; paqr9^ecu17; paqr7a^ecu11 (TU)
Observed In:	chorion unfertilized egg chorion unfertilized egg yolk yolk yolk yolk granule
Stage Range:	1-cell to 30%-epiboly

Phenotype Detail

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 511, Wu, X.J., Liu, D.T., Chen, S., Hong, W., Zhu, Y., Impaired oocyte maturation and ovulation in membrane progestin receptor (mPR) knockouts in zebrafish, 110856, Copyright (2020) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.