FIGURE

Figure 3.

ID

ZDB-FIG-200605-3

Publication

Choe et al., 2020 - Trim45 is essential to the development of the diencephalon and eye in zebrafish embryos

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Figure 3.

Phenotypes of the embryos from the overexpression or knock-down of trim45 in zebrafish embryos. Bright-field images of live embryos observed at 24 hpf stage. Un-injected embryos were used as a control (A and A’). trim45 mRNA (50 pg), trim45-MO (5 ng), and a mixture of trim45-MO (10 ng) and trim45 mRNA (10 pg) were injected into one cell stage zebrafish embryos respectively. Overexpression of trim45 showed a slight size expansion of midbrain and eyes (B and B’). trim45 morphants showed shrinkage in the size of midbrain and eyes (C and C’). About 79% of embryos, which were co-injected with trim45 mRNA, restored the wild-type phenotype (D and D’). Red dots – eye. Scale bar – 200 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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