FIGURE

Figure 6

ID

ZDB-FIG-200523-42

Publication

Cheng et al., 2004 - Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors

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Figure 6

Conserved Residues in Activin Loop-β8 Region Confer Independence from EGF-CFC Coreceptors

Synthetic mRNAs (200 pg) encoding Sqt harboring multiple mutations from ActivinβB (shown in red) were injected into wild-type and MZoep embryos. gsc and ntl mRNA expression is shown at shield stage; animal pole views are dorsal to the right. Schematic is not drawn to scale. Note that the Sqt3 and Sqt5 constructs containing the Lys102–X–Asp104 motif and Asn99 insertion show weak expansion of ntl expression animally and dorsally in MZoep mutants.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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