FIGURE

FIGURE 1

ID

ZDB-FIG-200517-11

Publication

Gallardo-Fuentes et al., 2020 - Functional Conservation of Divergent p63-Bound cis-Regulatory Elements

Other Figures

All Figure Page

Back to All Figure Page

FIGURE 1

Sequence divergence but functional conservation of p63 binding between zebrafish and human. (A) p63 motif logo found by either motif enrichment (top) or de novo motif discovery (bottom) in p63 ChIP-seq from zebrafish embryos (left) and human keratinocytes (right). Enrichment p-value and percentage of targets with the motif are represented. (B) Venn diagram showing the overlap between p63 binding sites (BSs) in zebrafish and human conserved at the sequence level. (C) p63 motif enrichment (left) and percentage of targets with p63 motif (right) for total and conserved p63 BSs in zebrafish and human. (D) Venn diagrams showing the overlap between zebrafish p63-associated genes with human ortholog (left) or human p63-associated genes with zebrafish ortholog (right) from BSs in both species. P-values for overlap significance using the Hypergeometric test are shown. (E) Gene Ontology (GO) biological process term enrichment for zebrafish and human p63 BSs. Terms related to p63 known functions were selected. Total GO terms are shown in Supplementary Dataset.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Genet