ZFIN Figure: Isles et al., 2019, Fig. 2

ZFIN ID: ZDB-FIG-200513-21

ZFIN ID: ZDB-FIG-200513-21

Isles et al., 2019 - The CXCL12/CXCR4 Signaling Axis Retains Neutrophils at Inflammatory Sites in Zebrafish. Frontiers in immunology 10:1784 Full text @ Front Immunol

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	mitfa^w2/w2; i114Tg mitfa^w2/w2; i114Tg + CRISPR1-cxcl12a mitfa^w2/w2; i114Tg + CRISPR1-cxcr4b
Condition:	amputation: caudal fin
Knockdown Reagents:	CRISPR1-cxcl12a CRISPR1-cxcr4b
Observed In:	caudal fin regenerating fin neutrophil neutrophil aggregation
Stage Range:	Long-pec to Protruding-mouth

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
mitfa^w2/w2; i114Tg	amputation: caudal fin	Long-pec	neutrophil amount, normal
		Protruding-mouth	neutrophil amount, normal
mitfa^w2/w2; i114Tg + CRISPR1-cxcl12a	amputation: caudal fin	Long-pec	neutrophil aggregation spatial distribution of a process, abnormal
		Long-pec	neutrophil decreased amount, abnormal
		Protruding-mouth	neutrophil aggregation spatial distribution of a process, abnormal
mitfa^w2/w2; i114Tg + CRISPR1-cxcr4b	amputation: caudal fin	Long-pec	caudal fin regenerating fin increased accumulation neutrophil, abnormal
		Long-pec	neutrophil aggregation spatial distribution of a process, abnormal
		Protruding-mouth	neutrophil aggregation spatial distribution of a process, abnormal

Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Immunol