FIGURE

Figure 2

ID

ZDB-FIG-200325-34

Publication

Zambusi et al., 2020 - Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon

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Figure 2

Grna; Grnb-deficient microglial cells display morphological changes associated with aging. (a–d) Micrographs depicting 4C4⁺ microglial cells. (a′–d′) Magnifications of boxed areas in (a–d), respectively. (a″–d″) Morphological tracing of 4C4⁺ microglial cells. Scale bars: 100 µm (a–d magnification) and 20 µm (a′–d′). (e–g) Morphological analysis depicting the average process length (e), number of main processes (f) and area of somata (g) of 4C4⁺ microglial cells. n.s, not significant, * p ≤ 0.05, **** p ≤ 0.0001, each data point represents a single cell (a total of 80 cells from four telencephali were analysed in each group).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	grna^{mde54a/mde54a}; grnb^{mde360/mde360}
Observed In:	microglial cell cell body microglial cell glial cell projection telencephalon microglial cell
Stage:	Adult

Phenotype Detail

Acknowledgments

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