FIGURE

Fig. 2.

ID

ZDB-FIG-191230-493

Publication

Ding et al., 2019 - Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2.

The bag3^e2/e2 mutant manifests a cardiac dysfunction phenotype. (A,B) Blood flow indices measured using a custom 30 MHz ultrasound probe. n=8-10, Student's t-test. (C) Examples of echocardiography images extracted from movies of beating hearts in WT controls and bag3^e2/e2 mutants at systole (upper panel) and diastole (lower panel). (D) Quantification of cardiac function indices measured by echocardiography in the bag3^e2/e2 mutant and WT control at 6 months. n=8, Student's t-test. (E-J) Cardiac pump function indices as measured by ex vivo heart pump function assay. n=12-13, Student's t-test. Data are mean±s.e.m.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	bag3^xu083/xu083
Observed In:	cardiac ventricle heart heart contraction myocardium
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.