FIGURE

Fig. 1

ID

ZDB-FIG-190723-1418

Publication

Chapman et al., 2019 - A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis

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Fig. 1

KRI-1 regulates MPK-1/ERK1 in the germline. a Di-phosphorylated MPK-1 in the germlines of wild type, kri-1(ok1251), and kri-1(ok1251); mpk-2(ok219) animals is measured along the midline from the distal to proximal end. The red box on each graph corresponds to the pachytene region. Images are representative of at least 30 worms per strain, per condition (×400 magnification). Scale bar is 25 μm. b IR-induced germline apoptosis scored in wild type, lip-1(zh15), kri-1(ok1251), and kri-1(ok1251); lip-1(zh15) animals (n ≥ 60). Red line is mean ± standard deviation. *P < 0.05, two-sided, unpaired t-test. c Schematic of intestinal KRI-1 regulating MPK-1/ERK1 in the germline

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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