ZFIN ID: ZDB-FIG-190702-2
Girotto et al., 2019 - Next Generation Sequencing and Animal Models Reveal SLC9A3R1 as a New Gene Involved in Human Age-Related Hearing Loss. Frontiers in genetics   10:142 Full text @ Front Genet
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: Day 6
PHENOTYPE:
Fish:
Observed In:
Stage: Day 6

Fig. 6

Hair cells number, morphology and orientation in Zebrafish larvae. (A) 3D reconstruction of the saccular macula. Hair cells are marked with GFP. FM1-43FX dye labels only mature and fully functional hair cells. (B) Saccular hair cells count in slc9a3r1 larvae (number of tested animals: slc9a3r1+/+N = 9, slc9a3r1+/- N = 10, slc9a3r1R180Q/R180Q N = 6). (C) 3D reconstruction of the saccular hair cell layer. brn3c:mGFP signal labels the membrane of the hair cells while red signal labels the kinocilia. (D) Hair cell polarization within the saccular macula of slc9a3r1 KI and their wt siblings.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
GFP s356tTg standard conditions Day 6 macula saccule hair cell IFL
slc9a3r1aze001/ze001; s356tTg standard conditions Day 6 macula saccule hair cell IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
slc9a3r1aze001/ze001; s356tTg standard conditions Day 6 macula saccule hair cell morphology, normal
Day 6 macula saccule has normal numbers of parts of type hair cell, normal
Acknowledgments:
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