FIGURE

Fig. 6

ID

ZDB-FIG-190701-25

Publication

Singh et al., 2019 - High glucose levels affect retinal patterning during zebrafish embryogenesis

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Fig. 6

Long-term implications of high-glucose exposure during embryonic stages in the adult zebrafish retina. (a) Retinal vasculature of Tg (fli1:EGFP) zebrafish adults (100 dpf) exposed to vehicle, 4 and 5% D-Glucose from 3 hpf until 5 dpf in a pulsatile manner. 4 and 5% D-Glucose treated group exhibited an increase in the number of hyaloid blood vessel sprouts (indicated by white arrows). (b) Statistical analysis of the number of blood vessel demonstrated a significant increase in the number of hyaloid blood vessel sprouts. Error bars indicate mean ± s.e.m.; Statistical differences were computed using two-tailed student’s t-test and are indicated as *p = 0.02, **p = 0.003; (n = 5). Scale bar, 100 µm. Images inverted to grayscale.

Expression Data

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Antibody Labeling

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Acknowledgments

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