FIGURE

Fig. 7

ID

ZDB-FIG-190701-14

Publication

Cal et al., 2019 - Countershading in zebrafish results from an Asip1 controlled dorsoventral gradient of pigment cell differentiation

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Fig. 7

Functional rescue of CRISPR-mediated asip1 mutation. Lateral (A,D,G,J), dorsal (B,E,H,K) and ventral-belly (C,F,I,L) views of 160 dpf WT, asip1-Tg, asip1^K.O., and asip1^K.O; asip1-Tg zebrafish. The pigment pattern of WT zebrafish shows (A) normal striped pattern, (B) dark dorsum and (C) light belly. The pigment pattern of asip1-Tg fish shows (D) almost normal striped pattern, although dark stripe 2D??? is rather thinner???, (E) hypopigmented dorsum and (F) light belly. The pigment pattern of asip1^K.O. fish shows (F) almost normal striped pattern, but with dark stripes 2 V and 3 V more developed than WT fish, (H) pigmented dorsum similar to WT and (I) hyperpigmented belly compared to WT. The asip1^K.O + asip1 − Tg phenotype shows a phenotype similar to the asip1 − Tg zebrafish, except that dark stripe 2D is more prominent. Scale bar: 5 mm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	asip1^iim08/iim08 iim05Tg asip1^iim08; iim05Tg
Observed In:	head ventral surface iridophore melanocyte melanophore stripe trunk dorsal surface trunk ventral surface xanthophore
Stage:	Adult

Phenotype Detail

Acknowledgments

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