FIGURE

Fig. 6

ID

ZDB-FIG-190604-12

Publication

Kopton et al., 2018 - Cardiac Electrophysiological Effects of Light-Activated Chloride Channels

Other Figures

Fig. 5
Fig. 6

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Fig. 6

GtACR1 activation can inhibit ventricular myocyte action potentials in isolated zebrafish hearts. In a subset of 3-months post fertilization (mpf) isolated zebrafish hearts (n = 3/7), a 0.16 mm² spot of 531/22 nm light applied to some eGFP expressing regions locally inhibited AP by depolarization of membrane potential, while there was no effect in regions with no eGFP expression (confirmed by live confocal microscopy).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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