Fig. 10
- ID
- ZDB-FIG-190528-16
- Publication
- Blokhina et al., 2019 - The telomere bouquet is a hub where meiotic double-strand breaks, synapsis, and stable homolog juxtaposition are coordinated in the zebrafish, Danio rerio
- Other Figures
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spo11 -/- males do not produce sperm, while spo11 -/- females produce offspring that show a spectrum of abnormalities. A: 1A-2A: Light microscope images of whole testes with spo11 -/- males showing a more translucent testis appearance as compared to WT. 3A-4C: Whole mount testes from WT and spo11 -/- males stained for Vasa (magenta) and DNA (DAPI, gray). Sperm clusters, indicated with "S" in WT, are absent in spo11 -/- mutants. B: Examples of offspring from spo11 -/- females showing the range of abnormalities at 28 hpf. hpf = hours post fertilization. C-D: Test crosses of spo11 -/- females (black circles) and WT control females (white circles) with WT males. Each circle represents a single test cross outcome. The data was pooled from two separate test crosses done on different days. The WT data at 5 dpf was assessed from one of the test crosses but was not tracked up to 5 days for the other WT test cross. C: spo11 -/- females produced similar numbers of eggs to WT females. D: The percent of eggs that were fertilized, and the percent of offspring that were normal or near normal in their development at 1 dpf, and at 5dpf. dpf = days post fertilization.
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| Stage: | Adult |
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| Stage Range: | Prim-5 to Adult |