FIGURE

Fig. 5

ID

ZDB-FIG-190404-19

Publication

Weijts et al., 2018 - Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos

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Fig. 5

Arterial blood flow activates Notch signaling in ISVs. Panels (a?d) show lateral images of zebrafish embryos with anterior side facing left. ECs express lifeact-mCherry. Notch signaling is reported by the expression of destabilized GFP (d2GFP) under the control of 12xCSL Notch responsive elements. Red arrows point to arterial ISVs. Orange arrows indicate the direction of blood flow. White arrowheads highlight ISVs without blood flow. Scale bars are 25??m. The numbers are averages � SEM. P?

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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