FIGURE

Fig. 1

ID

ZDB-FIG-190201-30

Publication

Joshi et al., 2018 - Mutation of a serine near the catalytic site of the choline acetyltransferase a gene almost completely abolishes motility of the zebrafish embryo

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Fig. 1

Phenotype of chata^tk64.

Wild-type embryo (A), chata^tk64 mutant 3 hours after de-chorionation (B) and immediately after de-chorionation (C). Note that (B) is indistinguishable from (A). Birefringence is similar in wild-type (D) and chata^tk64 mutant (E). Immunohistochemistry with phalloidin (red) marking F-actin, and α-actinin (green) (F, G), β-sarcoglycan (H, I) and α-bungarotoxin (J, K) do not reveal differences between wild-type (G, I, K) and chata^tk64 mutant (F, H, J) at 48 hpf.

Expression Data

Gene:	chrna1
Antibody:	Ab1-actn
Fish:	AB chata^tk64/tk64 (AB)
Anatomical Terms:	myotome acetylcholine-gated channel complex myotome Z disc skeletal muscle cell acetylcholine-gated channel complex skeletal muscle cell Z disc
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	chata^tk64/tk64 (AB)
Observed In:	myotome myofibril assembly myotome sarcomere organization skeletal muscle cell sarcomere skeletal muscle cell skeletal muscle myofibril
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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