ZFIN ID: ZDB-FIG-181108-23
Matsuda et al., 2017 - Thyroid Hormone Coordinates Pancreatic Islet Maturation During the Zebrafish Larval to Juvenile Transition to Maintain Glucose Homeostasis. Diabetes   66(10):2623-2635 Full text @ Diabetes
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Terms:
Stage Range: Day 6 to Days 7-13
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: Day 6 to Days 7-13

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
arxa WT chemical treatment by environment: 3,3',5'-triiodothyronine Day 6 whole organism RTPCR
EGFP nl1Tg control Days 7-13 primary islet IFL
nl1Tg chemical treatment by environment: 3,3',5'-triiodothyronine Days 7-13 primary islet IFL
GFP ml5Tg control Days 7-13 primary islet IFL
ml5Tg chemical treatment by environment: 3,3',5'-triiodothyronine Days 7-13 primary islet IFL
ulg515Tg control Days 7-13 primary islet IFL
ulg515Tg chemical treatment by environment: 3,3',5'-triiodothyronine Days 7-13 primary islet IFL
mnx1 WT chemical treatment by environment: 3,3',5'-triiodothyronine Day 6 whole organism RTPCR
pax4 WT chemical treatment by environment: 3,3',5'-triiodothyronine Day 6 whole organism RTPCR
pax6b WT chemical treatment by environment: 3,3',5'-triiodothyronine Day 6 whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment by environment: 3,3',5'-triiodothyronine Day 6 whole organism arxa expression decreased amount, abnormal
Day 6 whole organism mnx1 expression increased amount, abnormal
Day 6 whole organism pax4 expression increased amount, abnormal
Day 6 whole organism pax6b expression increased amount, abnormal
ml5Tg chemical treatment by environment: 3,3',5'-triiodothyronine Days 7-13 primary islet GFP expression increased amount, abnormal
ulg515Tg chemical treatment by environment: 3,3',5'-triiodothyronine Days 7-13 primary islet GFP expression increased amount, abnormal
Full text @ Diabetes