FIGURE

Fig. S8

ID

ZDB-FIG-181017-14

Publication

Liu et al., 2018 - Nodal signaling has dual roles in fate specification and directed migration during germ layer segregation

Other Figures

All Figure Page

Back to All Figure Page

Fig. S8

Nodal signaling inhibitor SB505124 blocks acvr1ba*-expressing cells from sorting.

(A) Representative images of sox17:GFP expression under 0, 25 μM or 50 μM SB505124. Drug treatment began at 6 hpf, images were taken at 10 hpf. Animal pole view. (B) Quantification of sox17:GFP fluorescence intensity under 0, 25 μM or 50 μM SB505124. *** p<0.001. n=3. (C) sox17:GFP expression for embryos with or without injection of acvr1ba* and under no drug treatment or treated 50 μM drug SB505124 treatment. (D) Transplant of acvr1ba*-expressing cells into sox17:GFP background under DMSO control and 50 μM drug SB505124 treatment at 18hfp.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development