FIGURE
Fig. 2
- ID
- ZDB-FIG-180921-9
- Publication
- Zhou et al., 2018 - Mutant MAPK7-Induced Idiopathic Scoliosis is Linked to Impaired Osteogenesis
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Fig. 2
Mapk7-morpholino knockdown zebrafish embryos exhibited body curvature. (A) Schematic diagram of the targeting site of mapk7-MO. (B) RT-PCR analysis of the mapk7 MO-injected embryos showed that exon 5 of mapk7 was skipped. (C and D) Body curvature was observed in the morphants, and co-injection of human WT MAPK7 mRNA significantly reversed the phenotype. Scale Bar: 500 μm. N≥100. (E and F) The number of ossified vertebrae in the morphants decreased significantly in response to the mapk7-morpholinos. ***P< 0.01. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage Range: | Day 4 to Days 14-20 |
Phenotype Detail
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Full text @ Cell Physiol. Biochem.