Fig. S3
Slower growth of aqp0a/b double mutant zebrafish lenses. (A) Zebrafish standard length (snout to start of tail) was used to determine developmental stage in juvenile-adult fish. (B) Post-embryonic double mutant lenses grow more slowly than WT or single aqp0 mutants (p-values for estimated difference in estimated regression slopes: WT vs double mutant 0.000769; double mutant vs aqp0a-/- 6.87e-05; double mutant vs aqp0b-/- 0.00114; see Supp. Figure 1). (C) Eye growth rate was unaffected in the mutants, thus the lens diameter versus eye diameter also revealed a slower lens growth compared to eye diameter fo the double mutants. |