FIGURE

Fig. S2

ID

ZDB-FIG-180828-24

Publication

Gauvrit et al., 2018 - HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development

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Fig. S2

zebrafish hhex mutants exhibit facial lymphatic defects at 5 dpf

(a-b) Facial lymphatic network of 5 dpf Tg(-5.2lyve1b:DsRed); hhex^+/+ and hhex^-/- larvae; hhex^-/- exhibit defects in facial lymphatic vessel formation (arrowheads indicate facial lymphatics, asterisks indicate lack of these structures in hhex mutant). (c-e) Percentage formation of lateral facial lymphatic (LFL) (c), otolithic lymphatic (OLV) (d) and branchial arch lymphatic (LAA) (e) in hhex^+/? (n=5) and hhex^-/- (n=5). Values represent means ± s.e.m. ****P ? 0.0001, **P ?0.01 and *P ? 0.05 by t-test. Scale bars: 100 ?m.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hhex^s722/s722; nz101Tg
Observed In:	facial lymphatic vessel otolithic lymph vessel
Stage:	Day 5

Phenotype Detail

Acknowledgments

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