FIGURE

Fig. 2

ID
ZDB-FIG-180827-78
Publication
Tseng et al., 2018 - Modeling Niemann-Pick disease type C1 in zebrafish: a robust platform for in vivo screening of candidate therapeutic compounds.
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Fig. 2

npc1 mutant zebrafish morphology and survival. (A) Photographs of representative wild-type and npc1m/m at 6 dpf and 7 weeks of age. No dysmorphology was noted at 6 dpf. Marked growth retardation was apparent at 7 weeks of age. Scale bars: 1 mm (6 dpf) and 5 mm (7 weeks). (B) Genotype distribution from the intercross of npc1+/m zebrafish at 6 dpf (n=166) and 7 weeks (n=82) of age. (C) Total length of npc1+/+, npc1+/m and npc1m/m zebrafish at 7 weeks of age. ***P<0.001 by two-tailed t-test.
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage Range: Day 6 to Days 45-89

Phenotype Detail
Acknowledgments
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