Fig. S8
- ID
- ZDB-FIG-180730-17
- Publication
- Than-Trong et al., 2018 - Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signaling cascade in the vertebrate adult brain
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Overexpression of hey1 decreases proliferation in adult RG. Electroporation of pCMV5:nlsgfp (A,B) or pCMV5:hey1-P2A-nlsgfp (A,C) in the adult ventricular zone and quantification of the proportion of PCNA-positive RG among GFP-positive RG at 2 days postelectroporation (D). B,C: whole-mount hemispheres processed for triple immunocytochemistry (GS: gray, PCNA: magenta, GFP: green), with high magnifications of the boxed areas. n=5 brains for pCMV5:nlsgfp and n=7 brains for pCMV5:hey1-P2A-nlsgfp. 63 and 105 cells were counted respectively in each condition. p=0.033, Mann-Whitney test. |