FIGURE

Fig. 3

ID

ZDB-FIG-180713-41

Publication

Huang et al., 2018 - Mutation of IPO13 causes recessive ocular coloboma, microphthalmia, and cataract

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Fig. 3

a Lateral view of zebrafish larvae. Larvae injected with the highest does of ipo13 targeting MO at 5.0 ng/µL exhibit apparent spinal curvature and reduced eye size. Abnormalities were not observed in the low concentration groups. b Magnified lateral pictures of zebrafish eyeballs show significant decrease in eye size. c Vertical view of larval eyeballs displays shorter axial length in the highest MO dose group. d, e Quantification of the eyeball axial length (d) and eye area (e). The axial length and eye area are represented as a white line and red circle, respectively. Student’s t-test, values are means ± s.e.m. ***P < 0.001

Expression Data

Antibody:	zpr-1
Fish:	AB + MO1-ipo13b
Knockdown Reagent:	MO1-ipo13b
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-ipo13b
Knockdown Reagent:	MO1-ipo13b
Observed In:	eye retinal inner plexiform layer retinal outer plexiform layer trunk
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Exp. Mol. Med.