ZFIN ID: ZDB-FIG-180705-79
Marin-Valencia et al., 2017 - A homozygous founder mutation in TRAPPC6B associates with a neurodevelopmental disorder characterised by microcephaly, epilepsy and autistic features.. Journal of Medical Genetics   55(1):48-54 Full text @ J. Med. Genet.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage Range: Long-pec to Day 5

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-trappc6b standard conditions Long-pec head decreased size, abnormal
Long-pec whole organism length, normal
Day 5 head decreased size, abnormal
Day 5 whole organism decreased life span, abnormal
Day 5 whole organism length, normal
WT + MO2-trappc6b standard conditions Long-pec head decreased size, abnormal
Long-pec whole organism length, normal
Day 5 head decreased size, abnormal
Day 5 whole organism length, normal
zf498Tg + MO1-trappc6b chemical treatment by environment: pentetrazol Day 5 neuron functionality, abnormal
Day 5 neuronal action potential process quality, abnormal
Full text @ J. Med. Genet.