FIGURE

Fig. S3

ID

ZDB-FIG-180703-55

Publication

Sorrells et al., 2018 - Spliceosomal components protect embryonic neurons from R-loop-mediated DNA damage and apoptosis

Other Figures

(all 7)

All Figure Page

Back to All Figure Page

Fig. S3

The splicing factor mutant sf3b1^hi3394 have elevated levels of H3S10P.

(A) Embryos were analyzed at 31 hpf by whole-mount immunofluorescence to detect histone H3 phosphorylation at serine 10 (H3S10P). Arrowheads mark increased H3S10P staining in the head of the sf3b1^hi3394aTg mutants. Magnified representative images of neural tissue highlighting differences in staining. (B) Neural tissue from the tails of sf3b1^hi3394aTgmutants and siblings was quantified for intensity of H3S10P staining and normalized to the average number of H3S10P positive puncta per sibling control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.