Fig. S3
- ID
- ZDB-FIG-180530-2
- Publication
- Tu et al., 2017 - Up-regulation of golgi ?-mannosidase IA and down-regulation of golgi ?-mannosidase IC activates unfolded protein response during hepatocarcinogenesis
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Examination of the Progression of Hepatocarcinogenesis in MAN1A1 and MAN1C1 Overexpressing Transgenic and WT Fish by Oil Red O and Sirius Red Staining. Frozen liver sections were used for staining (A) The signal present in MAN1A1 overexpressing transgenic fish starts at 3M but not in MAN1C1 transgenic fish and EGFP-mCherry control fish as measured by Oil Red O staining. (B) For Sirius Red staining, the signal in MAN1A1 overexpressing transgenic fish started at 3M and increased by 5M. In contrast, all MAN1C1 overexpressing transgenic fish and EGFP-mCherry control fish are normal. The images were taken at 400X magnification and the scale shown is 30 ?m. N=5 each stage per transgenic line. |