ZFIN ID: ZDB-FIG-180412-33
Carapito et al., 2017 - Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features. The Journal of Clinical Investigation   127(11):4090-4103 Full text @ Journal of Clin. Invest.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Knockdown Reagent:
Observed In:
Stage: Long-pec

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
i114Tg + MO1-srp54 amputation: caudal fin Long-pec post-vent region neutrophil decreased amount, abnormal
Long-pec post-vent region neutrophil chemotaxis disrupted, abnormal
i114Tg; nz50Tg + MO1-srp54 amputation: caudal fin Long-pec post-vent region neutrophil decreased amount, abnormal
Long-pec post-vent region neutrophil chemotaxis disrupted, abnormal
nz50Tg + MO1-srp54 amputation: caudal fin Long-pec post-vent region neutrophil decreased amount, abnormal
Long-pec post-vent region neutrophil chemotaxis disrupted, abnormal
Full text @ Journal of Clin. Invest.