FIGURE

Fig. 3

ID

ZDB-FIG-180410-43

Publication

Sun et al., 2017 - Proximal Tubular Expression Patterns of Megalin and Cubilin in Proteinuric Nephropathies

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Fig. 3

Immunoelectron microscopy images of megalin expression. Images are from IgA nephropathy (IgAN) patients with microalbuminuria (<300 mg/24 hours), macroalbuminuria (>300 mg/24 hours and <3500 mg/24 hours), nephrotic-albuminuria (>3500 mg/24 hours), and controls. The different expression of megalin between the 3 groups is shown in the brush border (left panel) of the proximal tubular cells and in the cytoplasm area (right panel) (original magnification ×39,000). Images (a) and (b) show nephrotic-albuminuric IgAN, (c) and (d) show macroalbuminuric IgAN, (e) and (f) show those with microalbuminuria, and (g) and (h) show controls. Note the increased labeling between the 3 groups. Bar = 200 nm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Kidney Int Rep