FIGURE

Fig. S2

ID

ZDB-FIG-180125-12

Publication

Li et al., 2017 - Discovery of a ROCK inhibitor, FPND, which prevents cerebral hemorrhage through maintaining vascular integrity by interference with VE-cadherin

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Fig. S2

FPND prevented atorvastatin-induced zebrafish cerebral hemorrhage as shown by o-dianizidine staining. The 22 dpf embryos were pretreated with either 0.1% DMSO (solvent) (A, a, B, b), 10 (C, c), 30 (D, d) or 100 ?M (E, e) FPND for 3 hours and replaced with 0.1% DMSO (A, a) or 2 ?M atorvastatin (B-E, b-E) for 24 h. The embryos were treated with 0.1% DMSO (solvent) served as normal control group (A). The asterisks indicate the erythrocyte accumulation in cerebral hemorrhage region in zebrafish head. Red scale bar represents 200 ?m.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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