FIGURE

Fig. 3

ID

ZDB-FIG-180104-54

Publication

Zhang et al., 2017 - Fatty Acid Binding Protein 11a Is Required for Brain Vessel Integrity in Zebrafish

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Fig. 3

fabp11a knockout leads to zebrafish brain hemorrhage. (A) Confocal imaging analysis of brain vascular morphology in control and fabp11a mutants Tg(kdrl:EGFP) embryos at 48 hpf. (B) Microscopy analysis of control embryos and fabp11a mutants in bright field at 48 hpf. Blue arrowheads indicate hemorrhage in zebrafish head. (C) Microscope analysis of control embryos and fabp11a mutants with O-dianisidine staining in bright field at 48 hpf. Blue arrowheads indicate hemorrhage in zebrafish head. (D) Fluorescent microscopy imaging of Tg(gata1:DsRed) embryos at 48 hpf. Scale bar: 20 ?m.

Expression Data

Genes:	DsRed EGFP
Fish:	s843Tg sd2Tg s843Tg + CRISPR1-fabp4a sd2Tg + CRISPR1-fabp4a
Knockdown Reagent:	CRISPR1-fabp4a
Anatomical Terms:	blood brain vasculature
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + CRISPR1-fabp4a sd2Tg + CRISPR1-fabp4a
Knockdown Reagent:	CRISPR1-fabp4a
Observed In:	brain brain blood
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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