FIGURE
Fig. 7
Fig. 7
CA-4 treatment caused norch1a up regulation. (A) Whole-mount in situ hybridization analysis of notch1a expression in control embryo and CA-4-treated embryo. Red arrowhead indicates neural tube. (B) RT-PCR analysis of notch1a expression in control embryo and CA-4-treated embryo. (C) Real-time PCR analysis of notch1a expression in control embryo and CA-4-treated embryo. (D) Confocal analysis of CA-4-treated Tg (huc:EGFP) embryo. (E) Statistical analyses of EGFP positive cells in central nervous system of control, CA-4-treated, CA-4 and DAPT treated, and CA-4 treated p53 knockdown embryo. (n?=?6), ***P?<?0.001. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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