FIGURE

Fig. 3

ID

ZDB-FIG-171027-26

Publication

Jing et al., 2015 - A feedback regulatory loop involving p53/miR-200 and growth hormone endocrine axis controls embryo size of zebrafish

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Fig. 3

miR-200 s regulate somatic growth in zebrafish embryo.

(A) Representative fish at 72hpf following injection with miRNA mimics and their inhibitors. (B) Body lengths (jaw to tail fin) of zebrafish embryos at 72hpf showed a dose-dependent suppression of somatic growth following ectopic expression of miR-141/429a mimics, and co-injection of miR-141/429a inhibitors partially rescued the growth defect. The indicated concentration of control mimic and inhibitor were used as control for the miR-141/429a mimics and inhibitors, and they have no obvious toxic effect on the embryo development. Error bars indicate mean ± SD, n = 30. Student’s t-test was used for statistical analysis (*p < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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