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ZIRC
ZFIN ID: ZDB-FIG-170927-37
Haskell et al., 2017 - Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease. Circulation. Cardiovascular genetics   10(3):e001443 Full text @ Circ Cardiovasc Genet
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Long-pec to Protruding-mouth

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-nup37 standard conditions Protruding-mouth pericardium edematous, abnormal
WT + MO1-nup43 standard conditions Protruding-mouth heart linear, abnormal
Protruding-mouth heart contraction decreased rate, abnormal
Protruding-mouth heart looping disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
WT + MO1-syne1b standard conditions Protruding-mouth pericardium edematous, abnormal
Protruding-mouth post-vent region increased curvature, abnormal
WT + MO2-nup37 standard conditions Protruding-mouth pericardium edematous, abnormal
WT + MO2-nup43 standard conditions Protruding-mouth heart linear, abnormal
Protruding-mouth heart contraction decreased rate, abnormal
Protruding-mouth heart looping disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
WT + MO2-syne1b standard conditions Protruding-mouth pericardium edematous, abnormal
Protruding-mouth post-vent region increased curvature, abnormal
twu26Tg + MO1-nup37 standard conditions Protruding-mouth heart morphology, abnormal
Protruding-mouth heart looping disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
twu26Tg + MO1-nup43 standard conditions Long-pec heart contraction decreased rate, abnormal
Protruding-mouth heart morphology, abnormal
Protruding-mouth heart contraction decreased rate, abnormal
Protruding-mouth heart looping disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
twu26Tg + MO1-syne1b standard conditions Protruding-mouth heart morphology, abnormal
Protruding-mouth heart looping disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
twu26Tg + MO2-nup37 standard conditions Protruding-mouth heart morphology, abnormal
Protruding-mouth heart looping disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
twu26Tg + MO2-nup43 standard conditions Long-pec heart contraction decreased rate, abnormal
Protruding-mouth heart morphology, abnormal
Protruding-mouth heart contraction decreased rate, abnormal
Protruding-mouth heart looping disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
twu26Tg + MO2-syne1b standard conditions Protruding-mouth heart morphology, abnormal
Protruding-mouth heart looping disrupted, abnormal
Protruding-mouth pericardium edematous, abnormal
Full text @ Circ Cardiovasc Genet