FIGURE

Fig. 5

ID

ZDB-FIG-170703-6

Publication

McArthur et al., 2017 - Key Features of Structural and Functional Organization of Zebrafish Facial Motor Neurons Are Resilient to Disruption of Neuronal Migration

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Fig. 5

Whole-Cell Recordings Show that Rhythmic and Swim-Related Activity Exhibited by Wild-Type FBMNs Is Also Present in Migration Mutant FBMNs

(A) Whole-cell patch-clamp recordings were made from the ventrolateral arm of the facial motor nucleus.

(B) These recordings reveal a subset of wild-type FBMNs (n = 8/23 cells) that burst infrequently, correlated with tail motor activity.

(C) Other wild-type FBMNs also exhibit rhythmic bursting, typically in the absence of tail motor activity (n = 15/23 cells).

(D) Migration mutant llk(rw16) FBMNs can also respond during attempted tail movements (infrequent bursts only: n = 2/8 cells) and in rhythmic bursts without large tail motor activity (n = 6/8 cells). All recordings were done at 5 dpf. Arrows indicate bursts of attempted tail movement activity.

(E) Box-whisker plot showing the distribution of median rhythmic inter-burst intervals in wild-type (n = 15 cells) and llk(w16) mutant (n = 6 cells) larvae.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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