FIGURE

Fig. 4

ID

ZDB-FIG-170516-50

Publication

Sauteur et al., 2017 - Distinct and redundant functions of Esam and VE-cadherin during vascular morphogenesis

Other Figures

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Fig. 4

esama^ubs19; ve-cad^ubs8 double mutant tip cells cannot maintain cell-cell contacts. (A-F) Still images from Movie 8 of an esama^ubs19; ve-cad^ubs8 double mutant Tg(fli1ep:gal4ff)^ubs3, Tg(UAS:EGFP-UCHD)^ubs18, Tg(kdrl:mCherry-CAAX)^s916 embryo at around 32?hpf, anterior to the left. Single channels are shown in inversed contrast (green is EGFP-UCHD and red is mCherry-CAAX on left and right, respectively) and the merge is shown in the middle. Red arrowheads point to filopodial interactions (B) or resolved contacts (E); green arrowheads point to cell-cell bridges or forming junctions in (F). Scale bar: 10?µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cdh5^ubs8/ubs8; esama^ubs19/ubs19; s916Tg; ubs18Tg; ubs3Tg
Observed In:	actin cytoskeleton organization actin filament organization apical junction assembly cell adhesion involved in sprouting angiogenesis dorsal longitudinal anastomotic vessel blood vessel development endothelial tip cell actin filament bundle of filopodium endothelial tip cell cell adhesion
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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