FIGURE

Fig. 5

ID

ZDB-FIG-170503-6

Publication

Vibert et al., 2017 - An ongoing role for Wnt signaling in differentiating melanocytes in vivo

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Fig. 5

Inactivation of Wnt signaling during melanocyte differentiation enhances melanocyte clustering in posterior dorsal head. Tg(hsp70l:tcf3-deltaC-GFP) embryos were heat-shocked at 29, 36, 48, and 62 hpf and observed at 73 hpf (B, D, F, H) and compared to control non-heat-shocked transgenic Tg(hsp70l:tcf3-deltaC-GFP) (A, C, E, G). Note the enhanced clustering of melanocytes in the posterior part of the dorsal head in treated embryos (blue arrowheads); the normal distribution in this area in untreated controls is indicated by red arrows. Heat shock activation of Wnt inhibition consistently resulted in smaller heads and eyes. Scale bars: 100 μm.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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