FIGURE

Fig. 2

ID

ZDB-FIG-170213-9

Publication

Zhang et al., 2017 - ATP6V1H Deficiency Impairs Bone Development through Activation of MMP9 and MMP13

Other Figures

(all 10)

All Figure Page

Back to All Figure Page

Fig. 2

Bone but not cartilage cells are defective in atp6v1h-deficient zebrafish.

(A-B) shows an image of a 6 days post fertilization (dpf) wild type and mutant embryo with relatively normal gross morphology. (C-F) Day 6 and 8 wild type and mutant embryos showing reduction in bone detected by calcein staining (ventral view, bright fluorescent stains indicate calcified bone). In (G-H), double staining for cartilage and bone demonstrate reduction of mineralized bone (dark purple, arrows) but not cartilage (blue). A, C, E and G are wild type. B, D, F, and H are mutant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	atp6v1h^la439/la439
Observed In:	bone mineralization swim bladder
Stage Range:	Day 6 to Days 7-13

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.