ZFIN ID: ZDB-FIG-161201-18
Shin et al., 2016 - Vegfc acts through ERK to induce sprouting and differentiation of trunk lymphatic progenitors. Development (Cambridge, England)   143(20):3785-3795 Full text @ Development
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Day 5

Fig. 6

Signaling through Flt4 Y1226/7 is dispensable for normal lymphatic function. (A-D) Transmitted light images of live zebrafish larvae at 10 dpf (A,D) or 5 dpf (B,C). Genotype is indicated in each panel. Lateral views, anterior to the left, dorsal is up. Arrows denote edema surrounding the intestinal tract and heart, arrowheads indicate edema surrounding the eyes. (E) Proportion and numbers of larvae of the indicated genotype exhibiting edema at 5 dpf for vegfcum18 and flt4um131 or 10 dpf for flt4Y1226/7Δ. ***P<0.001.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
flt4um131/um131 standard conditions Day 5 digestive system anatomical region edematous, abnormal
Day 5 eye anatomical region edematous, abnormal
Day 5 heart anatomical region edematous, abnormal
Day 5 swim bladder inflation decreased occurrence, abnormal
vegfcum18/um18 standard conditions Day 5 digestive system anatomical region edematous, abnormal
Day 5 eye anatomical region edematous, abnormal
Day 5 heart anatomical region edematous, abnormal
Day 5 swim bladder inflation decreased occurrence, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development