FIGURE
            Fig. 5
- ID
- ZDB-FIG-161019-8
- Publication
- Ellis et al., 2016 - Experimental Dissection of Metalloproteinase Inhibition-Mediated and Toxic Effects of Phenanthroline on Zebrafish Development
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                        Fig. 5
                    
                    
                
                
            
        
        
    
        
            
            
| 
 PhN disrupts craniofacial neural crest. (A) Epifluorescence micrograph of the head of a 48 hpf Tg(sox10a:eGFP) embryo treated from 24 hpf with 10 µM PhE showing normal development of the craniofacial neural crest (arrowheads indicate the otic vesicle and jaw cartilage). Embryos treated with: (B) 5; (C) 10; (D) 25; and (E) 40 µM PhN, exhibiting progressively more severe defects in these structures. Arrowhead in (E) indicates presumptive pigment cells trapped below the epidermis. Scale bars are 200 µm. | 
                
                    
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                        Expression Detail
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Antibody Labeling
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype Data
                    
                    
                
                
            
        
        
    
        
            
            
            
            
    
    
                
                    
                        Phenotype Detail
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Acknowledgments
                    
                    
                
                
            
        
        
    
        
            
            
                
                    
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      Full text @ Int. J. Mol. Sci.
                
                
            
        
        
    
    
     
        