FIGURE

Fig. 4

ID

ZDB-FIG-160713-9

Publication

Daniele et al., 2016 - Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function

Other Figures

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Fig. 4

Loss of Wrb disrupts endogenous ribeye localization at synaptic ribbons in hair cells at 5 dpf. (A) Lateral image of 5 dpf larvae immunostained with ribeye b antibodies to label lateral line hair cells. Hair cells in rostral (a, a′), middle (b, b′), and caudal (c, c′) regions of the trunk were imaged by fluorescence microscopy. (B, C) Fluorescence images showing individual neuromasts immunolabeled with SV2 (red) and ribeye-b (green) antibodies in wild-type and wrb^-/- mutant larvae. Dotted outline in (B) depicts the orientation of individual hair cells within a single neuromast, as it relates to synaptic immunoreactivities.

Expression Data

Antibodies:	Ab-SV2 Ab1-ctbp2l
Fish:	WT get1^{hi1482Tg/hi1482Tg}
Anatomical Term:	neuromast hair cell
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	get1^{hi1482Tg/hi1482Tg}
Observed In:	neuromast hair cell
Stage:	Day 5

Phenotype Detail

Acknowledgments

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