FIGURE
Fig. 3
- ID
- ZDB-FIG-160330-11
- Publication
- McMillen et al., 2016 - A Sawtooth Pattern of Cadherin 2 Stability Mechanically Regulates Somite Morphogenesis
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Fig. 3
Coordinated Regulation of ECM Assembly by Cdh2 and Itgα5 (A and B) Lateral (A) and dorsal (B) views of the anterior paraxial mesoderm in 10- to 12-somite-stage embryos showing loss of somite borders and de-adhesion of cells in MZitgα5-/-;cdh2mo embryos (n = 8). (C) 3D dorsal projection of anterior paraxial mesoderm FN immunolocalization z stacks showing loss of dorsolateral FN in MZitgα5-/-;cdh2mo embryos. (D) Single dorsal z-slices of FN immunolocalization of posterior paraxial mesoderm showing globular FN in cdh2mo embryos and diffuse ectopic FN in MZitgα5-/-;cdh2mo embryos. Scale bars, 40 µm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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